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ORIGINAL ARTICLE
Year : 2021  |  Volume : 48  |  Issue : 2  |  Page : 79-92

Development of Bengali version of a questionnaire assessing impact of hyperuricemia on quality of life


1 Departments of Organon of Medicine and Homoeopathic Philosophy, The Calcutta Homoeopathic Medical College and Hospital, Kolkata, West Bengal, India
2 Department of Practice of Medicine, The Calcutta Homoeopathic Medical College and Hospital, Kolkata, West Bengal, India
3 Department of Community Medicine, D. N. De Homoeopathic Medical College and Hospital, Kolkata, West Bengal, India
4 Department of Materia Medica, National Institute of Homoeopathy, Under Ministry of AYUSH, Government of India, Kolkata, West Bengal, India
5 Department of Organon of Medicine and Homoeopathic Philosophy, D. N. De Homoeopathic Medical College and Hospital, Kolkata, West Bengal, India
6 Department of Organon of Medicine and Homoeopathic Philosophy, State National Homoeopathic Medical College and Hospital, Lucknow, Uttar Pradesh, India
7 Department of Repertory, D. N. De Homoeopathic Medical College and Hospital, Kolkata, West Bengal, India

Correspondence Address:
Sangita Saha
Department of Organon of Medicine and Homoeopathic Philosophy, The Calcutta Homoeopathic Medical College and Hospital, 265-266, Acharya Prafulla Chandra Road, Kolkata - 700 009, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jss.jss_114_20

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Context: Hyperuricemia and gout has been found to be associated with reduced health-related quality of life (HRQoL); however, there is no available Bengali questionnaire assessing the same. Aims: We aimed to develop the Bengali version of a questionnaire and examine its cross-cultural adaptability considering linguistic equivalence. Settings and Design: A multicentric, mixed methods, cross-sectional study was conducted through consecutive sampling at the outpatients of three homeopathic hospitals in West Bengal. Subjects and Methods: The Bengali version of the questionnaire was produced by standardized forward–backward translations. Psychometric analysis was run to examine its factor structure, validity, and reliability. Statistical Analysis Used: Reliability was examined using internal consistency (n = 210). Construct validity was examined by exploratory factor analysis (n = 105) using principal component analysis (PCA; varimax rotation). Subsequently, confirmatory factor analysis (CFA; n = 105) was performed to verify the model fit. Results: The internal consistency (Cronbach's α =0.880; 95% confidence interval 0.855–0.902), test–retest reliability and concurrent validity of the questionnaire– all were within acceptable limits. The (Kaiser–Meyer–Olkin = 0.832) and Bartlett's test of sphericity (Chi-square: 1644.344 at df = 210, P < 0.001) both suggested adequacy of the sample. In factor analysis using varimax, all the items loaded above the prespecified value of 0.4 and identified 6 components, explaining 77% of the variation. One item revealed a negative variance; hence the whole component of 2 items was removed from further evaluation. The goodness-of-fit of the 5-components model in CFA was also acceptable (Comparative fit index = 0.702, tucker Lewis index = 0.641, Root Mean Square Error of Approximation = 0.156, and Standardized Root Mean Square Residual = 0.123). Conclusions: The developed Bengali version of the questionnaire consisting of 19 items and framed within 5 components, appeared to be a valid and reliable instrument measuring HRQoL in patients suffering from hyperuricemia.


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