Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2022  |  Volume : 49  |  Issue : 1  |  Page : 12-16

Role and significance of ghrelin and leptin in hunger, satiety, and energy homeostasis


1 Department of Physiology, BJMC, Ahmedabad, Gujarat, India
2 Department of Pathology, FDS, MRIIRS, Faridabad, India
3 Department of Anatomy, SGT Medical College, Gurugram, Haryana, India

Correspondence Address:
Savita Bansal
Department of Pathology, FDS, MRIIRS, Faridabad - 121 004, Haryana
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jss.jss_126_21

Rights and Permissions

Hunger is a set of internal experiences that lead a human or animal to seek food. Satiety is a desire to limit further food intake or the state of being gratified after completing a meal. The objective of this review article is to discuss the influence of ghrelin and leptin in hunger, appetite, satiety, and long-term energy homeostasis. The data for this review were collected through an extensive journal search. Electronic databases (Medline and PubMed) were thoroughly consulted, and few articles were obtained from the website: Google Scholars (http://scholar.google.com). Ghrelin and leptin are concerned with food intake and energy homeostasis. Ghrelin increases food intake and affects food patterns, whereas leptin induces satiety. Circulating leptin levels are directly proportion to the amount of body fat, thereby reflecting the status of long-term energy stores. Recent work suggests that leptin plays a more important role in the maintenance of weight loss than weight loss per se and ghrelin increases appetite, adjusts energy balance, and enhances the release of growth hormone from the pituitary gland


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed445    
    Printed26    
    Emailed0    
    PDF Downloaded57    
    Comments [Add]    

Recommend this journal