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Year : 2022  |  Volume : 49  |  Issue : 2  |  Page : 186-189

Automated complete blood count profile as a probable indicator of dengue fever severity in children

1 Department of Pathology, DMGMC and H, Purulia, West Bengal, India
2 Department of Pediatrics, Dr. B C Roy PGIPS, Kolkata, West Bengal, India
3 Department of Anatomy, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India

Correspondence Address:
Arijit Majumdar
Vill Duilya, Charaktala, PO – Andul, District Howrah; Pin. 711 302, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jss.jss_135_21

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Background: Dengue is now endemic in more than 100 tropical and subtropical countries. Ninety percent of dengue hemorrhagic fever occurs in children <15 years of age. Leukopenia and thrombocytopenia near the end of the febrile phase are the common findings in dengue fever. Aims and Objectives: (1) To see any significant correlations between various hematological parameters with severity of dengue and (2) to see the shift in the values (increase/decrease) of platelet indices in dengue patients. Materials and Methods: One hundred and twenty patients admitted either with laboratory report of seropositive dengue or with dengue-like symptoms and who were found to be dengue positive after admission were included in the study. Complete hemogram including platelet indices was evaluated by an automated cell counter. Clinical examinations were performed in detail with special reference to the presence of warning signs such as vomiting, lethargy, pain abdomen, bleeding, and ascites. Results: Total leukocyte count, platelet distribution width, and mean platelet volume were not significantly different in patients with warning signs from those without it. The level of mean hematocrit was significantly higher and the mean plateletcrit was significantly lower in dengue with warning signs. Conclusions: Simultaneous measurement of complete blood count and platelet indices can provide us a valid instrument for the measurement of dengue disease severity and an insight into the potential etiology that resulted in change in platelet indices.

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